Wesker to the forefront

[Scream]

He had his head cut off? When? I remember him being impaled by the Tyrant but that's it.

In one of the endings you can find him in the power room near the self-destruct console with his head cut off (by a chimera).

As for Wesker being a failure, let's remember he can pwn anyone in a fight. The only reason he dies in RE5 would be because it would be weird to end the game with a gameover screen.

[progenitor]

Here's a conversation that Mr. Spencer (blue) and I (red) had on MSN (long time posters will remember him)

The Wesker Plan was a failure.
Considering that one of its key results was bested by Birkin, a mere unaltered human.
Birkin wasn't manipulated in any way, he was just a genius. Like I said, the Wesker Plan was an utter failure.
I mean, Wesker couldn't even keep up with Birkin.

In an evolutionary sense, Wesker didn't pass on his genes to any children

This so-called master race subject, struggling with an ordinary human.
I find it amusing.

so he's an evolutionary failure too. Birkin had a daughter

Yep, Birkin did.
Birkin single-handedly rendered the Wesker Plan a pointless waste of everyone's time.

Discuss

The Wesker Plan was the complete opposite of a failed design. Lord Spencer's overall plan was a failure, mostly because of his own paranoia. The Wesker Plan was designed to create the prototype of a new and evolved master race that would be the harbinger of the overall dream of Spencer's, an evolved world where he would be renowned as the god of it's creation. Albert Wesker, as an experiment, was a complete success. Spencer gathered genetically gifted children at a young age and exposed them to the Progenitor Virus, and the one and only gifted child with the immune system strong enough to bond with that virus was Albert Wesker himself.

Bear in mind; the West African Ndipaya tribe used the base of the Progenitor Virus from the flower it came from, known to them as the "Stairway to the Sun," in a ritualistic event in which they exposed their warriors to the potent flower containing the Progenitor Virus. It killed many, and the ones that were able to survive and bond with the virus were championed as leaders of the tribe, who, according to the legend, would inherit great strength.

Albert Wesker was genetically gifted from birth, which is why as he came to manhood, he was incredibly intelligent and cunning, enough that he was given the job as Umbrella researcher right alongside William Birkin. Wesker simply found the job tedious, which is why he transferred to the armed forces. William Birkin was far from superior to Wesker, in fact, Birkin took credit for the creation of the T-Virus after they oversaw the assassination of one James Marcus. Don't get me wrong, William Birkin was my favorite character for quite a long time, but even before he created the G-Virus, he was incredibly jealous and embittered due to the fact that Alexia Ashford was the new focus of Umbrella as the child prodigy in biological engineering, it was only after the "death" of Alexia that William Birkin was able to focus back to his work and create the G-Virus.

Even so, the G-Virus was far from a stable success. It was unstable, and although it was more promising than the T-Virus, it's mutation obsessed over reproducing with other genetically compatible subjects. Where is the superiority in a virus that's only concern is committing genetic incest? Over all, Albert Wesker became more of a successful story than William Birkin, yet both suffered a similar fate in that they infected themselves with their own viral design and were destroyed thereafter. The only true success that William Birkin created was the virus that Wesker took in the first Resident Evil , after staging his "death" at the hands of the tyrant. That viral strain was successful in that it bonded with Wesker's anatomy in that it upgraded all physical attributes, increasing his metabolism, his speed, strength, durability, and healing.

William Birkin failed as a father, failed as a husband, and in the end, caused his own demise. As awesome a character as William Birkin is, i'd hardly say he was in any way superior in story to Albert Wesker.

[5 Minutes]

"He and I still have time to continue our little game of cat and mouse before the next move is played."