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Since BH4 was released, I haven't been able to shake Luis Sera's "I think I've seen a sample of the virus at the lab at the department." It's so out of the blue, yet framed as though it is important.
Let's consider this. In the BIO series, gene manipulation has always been performed with the t-Virus based on the concept of genetic transduction via a retroviral vector, as it makes the process simple due to Progenitor having the latent ability to rewrite DNA in general. The virus was used as the vector to incorporate reptile and fly genes into a human ovum in order to create the Hunter and Chimera, for example.
We know now that the dominant species is artificially developed by incorporating the Salazar family's control of the Plaga via sound capability, while the mutagenic properties of the original Plaga are also strengthened and the host is able to maintain control. All done through gene manipulation. The "Plaga Type 2 & 3" models are the same, along with Belikova's synthetic species; all developed with gene manipulation upon the original Plaga. But we already know from the very beginning of the series that in this universe, the t-Virus is the ultimate tool for gene manipulation.
Under this line of thinking, it would mean that Del Lago, El Gigante, U-3, Verdugo, U-8, all of those lovable creatures, were actually created through application of the t-Virus on top of the Plaga, enhancing the mutagenic capacity of both. This would go some way to explain them rather than just "magic parasite" considering it incorporates knowledge we already have from the series. This would also explain why there are so many different-looking Plaga in all of the artificial creatures. These are also present in the island lab in beakers. They wouldn't need to store the regular Plaga in beakers when they have a limitless supply of eggs.
I don't know why the involvement of the t-Virus has never been outright stated. Perhaps they feel the mode of gene manipulation should be obvious to fans of the series? Perhaps Mikami took whatever material there was about it with him and the current developers are forced to leave it vague? Perhaps Mikami just didn't write anything about it but had it in mind? But honestly, it is the best explanation for all of this stuff.
Let's consider this. In the BIO series, gene manipulation has always been performed with the t-Virus based on the concept of genetic transduction via a retroviral vector, as it makes the process simple due to Progenitor having the latent ability to rewrite DNA in general. The virus was used as the vector to incorporate reptile and fly genes into a human ovum in order to create the Hunter and Chimera, for example.
We know now that the dominant species is artificially developed by incorporating the Salazar family's control of the Plaga via sound capability, while the mutagenic properties of the original Plaga are also strengthened and the host is able to maintain control. All done through gene manipulation. The "Plaga Type 2 & 3" models are the same, along with Belikova's synthetic species; all developed with gene manipulation upon the original Plaga. But we already know from the very beginning of the series that in this universe, the t-Virus is the ultimate tool for gene manipulation.
Under this line of thinking, it would mean that Del Lago, El Gigante, U-3, Verdugo, U-8, all of those lovable creatures, were actually created through application of the t-Virus on top of the Plaga, enhancing the mutagenic capacity of both. This would go some way to explain them rather than just "magic parasite" considering it incorporates knowledge we already have from the series. This would also explain why there are so many different-looking Plaga in all of the artificial creatures. These are also present in the island lab in beakers. They wouldn't need to store the regular Plaga in beakers when they have a limitless supply of eggs.
I don't know why the involvement of the t-Virus has never been outright stated. Perhaps they feel the mode of gene manipulation should be obvious to fans of the series? Perhaps Mikami took whatever material there was about it with him and the current developers are forced to leave it vague? Perhaps Mikami just didn't write anything about it but had it in mind? But honestly, it is the best explanation for all of this stuff.
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