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From an interview with Hideki Kamiya in the BIOHAZARD 2 Official Guidebook. Pg. 257-262. The rest of the interview (40 questions in total) is being translated still.
Other details in the interview thus far:
1) Sherry's name comes from a song by a band called 'The Four Seasons'.
2) Irons stuffed the officers he killed. He also had Ben thrown in jail, and made up a crime.
3) Irons and Kendo's names came directly from the first BIO HAZARD. Irons from the S.T.A.R.S. cards in the character selection screen,
4) Brad Vickers was a coward and sided with Irons in response to S.T.A.R.S., that's why he's still there in BH3.
Q21. The whereabouts of G was snatched from under the nose of William?
A21. Take a good look at Annette’s flashback scene and you’ll realize that William who went berserk took back all the G-virus samples and took them into his body through the mouth… In other words, he “ate” them. By the way, it’s believed that the G capsule which Hunk has in another scenario called “The 4th Survivor” was secured before it was eaten by William. As an outcome of that scenario, you may think that the G-virus was put into the hands of Umbrella by Hunk.
A21. Take a good look at Annette’s flashback scene and you’ll realize that William who went berserk took back all the G-virus samples and took them into his body through the mouth… In other words, he “ate” them. By the way, it’s believed that the G capsule which Hunk has in another scenario called “The 4th Survivor” was secured before it was eaten by William. As an outcome of that scenario, you may think that the G-virus was put into the hands of Umbrella by Hunk.
Q24. S.T.A.R.S. members don’t appear…?
Q24. I thought we needed a new main character, especially from the previous game… We decided to make a whole new story and what meant most is that we needed an attractive character not less than the previous game.
Q24. I thought we needed a new main character, especially from the previous game… We decided to make a whole new story and what meant most is that we needed an attractive character not less than the previous game.
Q33. Tell us about the rejected design.
A33. We planned to entwine Ada’s lover “John” into the sub-story. He supported the main character from the shadows to make amends for his involvement in the evil plans of Umbrella while his own body was being attacked by “T-virus” and entrusted the player with “anti T-virus ammo” to pierce Tyrant with the final blow at the end, and died without meeting Ada… For the zapping mode, whether John survived until the end or died depended on the player… How about that one? Should I have done it?
A33. We planned to entwine Ada’s lover “John” into the sub-story. He supported the main character from the shadows to make amends for his involvement in the evil plans of Umbrella while his own body was being attacked by “T-virus” and entrusted the player with “anti T-virus ammo” to pierce Tyrant with the final blow at the end, and died without meeting Ada… For the zapping mode, whether John survived until the end or died depended on the player… How about that one? Should I have done it?
1) Sherry's name comes from a song by a band called 'The Four Seasons'.
2) Irons stuffed the officers he killed. He also had Ben thrown in jail, and made up a crime.
3) Irons and Kendo's names came directly from the first BIO HAZARD. Irons from the S.T.A.R.S. cards in the character selection screen,
4) Brad Vickers was a coward and sided with Irons in response to S.T.A.R.S., that's why he's still there in BH3.
And because I didn't think he was the guy from RE1's final lab, I made him an Afro-american in my movie 
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